Mod GRF 1-29 (CJC-1295 No DAC)
Modified GRF (Mod GRF) 1-29, also known as CJC-1295 without DAC, is a truncated peptide analogue of growth hormone-releasing hormone (GHRH). Initially developed in the 1980s, Mod GRF has shown potential in enhancing muscle repair and growth, accelerating wound healing, strengthening bones, improving fat metabolism, and boosting overall metabolism. It also offers potential benefits in regulating blood sugar levels and supporting the immune system.
PEPTIDES LIST
- Adipotide (FTPP)
- AICAR
- AOD9604
- ARA-290
- B7-33
- BPC-157
- Bronchogen
- Cagrisema
- Cagrilintides
- Cardiogen
- Cartalax
- Cerebrolysin (215mg/ml, 10ml)
- Chonluten
- CJC-1295 DAC
- Cortagen
- DSIP
- Epithalon (Epitalon)
- Follistatin-315
- Follistatin-344
- FOXO4-DRI
- GHK-Cu (Copper Peptide)
- GHK Basic
- GHRP-2
- GHRP-6
- GHRH (GH-Releasing Hormone)
- Glutathione
- Gonadorelin (GnRH)
- GLP2 & GLP3
- hGH Fragment 176-191
- Hexarelin
- Humanin
- Ipamorelin
- Kisspeptin-10
- KPV (ACTH (11-13) alpha-MSH)
- Liraglutide (GLP-1 Analogue)
- Livagen
- LL-37 (CAP-18)
- Melanotan 2 (Melanotan II)
- Mezdutide
- MGF (C-terminal)
- ModGRF 1-29 (CJC-1295 No DAC)
- MK-677 (Ibutamoren)
- MOTS-c
- N-Acetyl Epithalon Amidate
- N-Acetyl Selank Amidate
- N-Acetyl Semax Amidate
- NAD+
- Ovagen
- Oxytocin+
- Pancragen
- PE-22-28
- PEG-MGF (Pegylated MGF)
- Pinealon
- PNC-27
- Prostamax
- PT-141 (Bremelanotide)
- P21 (P021)
- Retatrutide
- Snap8
- Tesa_Ipa_Blend
- Triblend
- Selank
- Semaglutide (GLP-1 Analogue)
- Semax
- Sermorelin
- SS-31
- Survodutide
- TB-500
- Tesamorelin
- Testagen
- Thymagen
- Thyrotropin-TRH
- Tirzepatide
- Triptorelin
- Vesugenas
- Vesilute
- Vilon
- VIP (Vasoactive Intestinal Peptide)
- GLP2
- GLP3
- Klow
- Klow8
- SLU-PP-332
- BAM-15
- Orforglipron
- Noopept
- 9-Me-BC
- Methylene Blue
- Lemon Bottle
Modified GRF (Mod GRF) 1-29, also known as CJC-1295 without DAC, is a truncated peptide analogue of growth hormone-releasing hormone (GHRH). Initially developed in the 1980s, Mod GRF has shown potential in enhancing muscle repair and growth, accelerating wound healing, strengthening bones, improving fat metabolism, and boosting overall metabolism. It also offers potential benefits in regulating blood sugar levels and supporting the immune system.
MOD-GRF 1-29 is described as a growth hormone–releasing hormone (GHRH) analogue and does not contain DAC (drug affinity complex). It was developed to help overcome the short half-life of natural GHRH, supporting a longer duration of action in stimulating growth hormone.
Research Notes (Mechanism/Context Summary):
• MOD-GRF 1-29 binds to GHRH receptors in the pituitary gland, promoting GH production.
• It’s described as helping maintain the natural rhythmic release of GH (supporting balanced physiology), and may influence downstream hormones like IGF-1.
• Combining MOD-GRF 1-29 with GHRPs is discussed as enhancing GH release by inhibiting somatostatin-related suppression, supporting more effective GH output.
• Additional research discussion includes potential roles in gut/inflammatory contexts and possible cardioprotective effects.
| Protocol Item | Guidance |
|---|---|
| Dose | 100 mcg per doseHigher doses have not been seen to produce a stronger response. |
| Cycling | 1–7× weekly, typically 8–12 weeks on, then 4–8 weeks off |
| Timing / Diet Note | Carbohydrates and fatty acids may blunt growth hormone release.Often taken 30 minutes before eating or 2 hours after eating. |
| Frequency Note | Multiple injections can be given in a day to increase GH secretion (noted in bodybuilding-focused use cases). |
Caution & Contraindications:
Caution:
• May cause water retention, hunger, headaches, changes in blood sugar levels, and joint pain
• Use caution in individuals with existing hormonal imbalances or related conditions
Contraindications:
• Individuals with active or a history of hormone-sensitive cancers
Reconstitution Options (Vial Format):
• 2 mg
• 5 mg
Reconstitution (General Handling):
• Use sterile technique and sanitize the vial stopper before access.
• Add diluent slowly along the vial wall to minimize foaming.
• Gently swirl/roll until fully dissolved (avoid vigorous shaking).
• Store according to the product label/spec sheet and protect from light as applicable.
Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
Molecular Formula: C152H252N44O42
Molar Mass: 3368.7 g/mol
Synonyms: Mod GRF 1-29, CJC-1295 no DAC
The above literature was researched, edited and organized by Dr. Logan, M.D. Dr. Logan holds a doctorate degree from https://case.edu/medicine/Case Western Reserve University School of Medicine and a B.S. in molecular biology.
Case Western Reserve University School of Medicine
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